The CIPRES Science Gateway (CSG) is a public resource created to provide access to community phylogenetics codes on high performance computing resources. The CSG has been in operation since 2009, and has a large and growing user base. As a popular resource, the CSG provides an opportunity to study user behavior and job submissions in a Gateway environment. Here we examine CSG user and data turnover, jobs submissions success rates, and causes for job failures. The results of our investigation provide a better understanding of the populations that use the CSG, and point to areas where improvements can be made in meeting user needs and using resources more efficiently.